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Phase II Trials in Drug Development and Adaptive Trial Design
Phase II clinical studies represent a critical point in determining drug costs, and phase II is a poor predictor of drug success: >30% of drugs entering phase II studies fail to progress, and >58% of drugs go on to fail in phase III. Adaptive clinical trial design has been proposed as a way to...
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| Pubblicato in: | JACC Basic Transl Sci |
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| Autore principale: | |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609997/ https://ncbi.nlm.nih.gov/pubmed/31312766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2019.02.005 |
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