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Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Part 2: Potential Alternatives to the Use of Animals in Preclinical Trials

Dramatically rising costs in drug development are in large part because of the high failure rates in clinical phase trials. The poor correlation of animal studies to human toxicity and efficacy have led many developers to question the value of requiring animal studies in determining which drugs shou...

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Detalles Bibliográficos
Publicado en:JACC Basic Transl Sci
Autor Principal: Van Norman, Gail A.
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2020
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185927/
https://ncbi.nlm.nih.gov/pubmed/32363250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.03.010
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