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Limitations of Animal Studies for Predicting Toxicity in Clinical Trials: Part 2: Potential Alternatives to the Use of Animals in Preclinical Trials

Dramatically rising costs in drug development are in large part because of the high failure rates in clinical phase trials. The poor correlation of animal studies to human toxicity and efficacy have led many developers to question the value of requiring animal studies in determining which drugs shou...

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Bibliografiske detaljer
Udgivet i:JACC Basic Transl Sci
Hovedforfatter: Van Norman, Gail A.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7185927/
https://ncbi.nlm.nih.gov/pubmed/32363250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacbts.2020.03.010
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