Systemically administered peptain-1 inhibits retinal ganglion cell death in animal models: implications for neuroprotection in glaucoma

Axonal degeneration and death of retinal ganglion cells (RGCs) are the primary causes of vision loss in glaucoma. In this study, we evaluated the efficacy of a peptide (peptain-1) that exhibits robust chaperone and anti-apoptotic activities against RGC loss in two rodent models and in cultured RGCs....

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:Cell Death Discov
Autors principals: Stankowska, Dorota L., Nam, Mi-Hyun, Nahomi, Rooban B., Chaphalkar, Renuka M., Nandi, Sandip K., Fudala, Rafal, Krishnamoorthy, Raghu R., Nagaraj, Ram H.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609721/
https://ncbi.nlm.nih.gov/pubmed/31285855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41420-019-0194-2
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars