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Inhibitors of DAG metabolism suppress CCR2 signalling in human monocytes
BACKGROUND AND PURPOSE: CCL2 is an inflammatory chemokine that stimulates the recruitment of monocytes into tissue via activation of the GPCR CCR2. EXPERIMENTAL APPROACH: Freshly isolated human monocytes and THP‐1 cells were used. Fura‐2 loaded cells were used to measure intracellular Ca(2+) respons...
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| Publicado no: | Br J Pharmacol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609539/ https://ncbi.nlm.nih.gov/pubmed/31032885 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14695 |
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