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P2Y(6) receptor inhibition perturbs CCL2-evoked signalling in human monocytic and peripheral blood mononuclear cells

The chemokine CCL2 serves to target circulating monocytes and other leukocytes to tissue during innate immune responses, and modulates the progression of chronic inflammatory disease through activation of the receptor CCR2. Here, we show that co-activation of the P2Y(6) purinergic receptor (encoded...

詳細記述

保存先:
書誌詳細
出版年:J Cell Sci
主要な著者: Campwala, Hinnah, Sexton, Darren W., Crossman, David C., Fountain, Samuel J.
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4231309/
https://ncbi.nlm.nih.gov/pubmed/25271060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.159012
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