Llwytho...

Inhibitors of DAG metabolism suppress CCR2 signalling in human monocytes

BACKGROUND AND PURPOSE: CCL2 is an inflammatory chemokine that stimulates the recruitment of monocytes into tissue via activation of the GPCR CCR2. EXPERIMENTAL APPROACH: Freshly isolated human monocytes and THP‐1 cells were used. Fura‐2 loaded cells were used to measure intracellular Ca(2+) respons...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Br J Pharmacol
Prif Awduron: Day, Priscilla, Burrows, Lisa, Richards, David, Fountain, Samuel J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609539/
https://ncbi.nlm.nih.gov/pubmed/31032885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14695
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