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C23, an Oligopeptide Derived from Cold-inducible RNA-binding Protein, Suppresses Inflammation and Reduces Lung Injury in Neonatal Sepsis
INTRODUCTION: Neonatal sepsis remains a leading cause of infant mortality. Cold-inducible RNA binding protein (CIRP) is an inflammatory mediator that induces TNF-α production in macrophages. C23 is a CIRP-derived peptide that blocks CIRP from binding its receptor. We therefore hypothesized that trea...
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| Publicado no: | J Pediatr Surg |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609502/ https://ncbi.nlm.nih.gov/pubmed/30691879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpedsurg.2018.12.020 |
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