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GGTase3 is a Newly Identified Geranylgeranyltransferase Targeting a Ubiquitin Ligase

Protein prenylation is believed to be catalyzed by three heterodimeric enzymes: FTase, GGTase1, GGTase2. Here, we report the identification of a previously unknown human prenyltransferase complex consisting of an orphan prenyltransferase α subunit, PTAR1, and the catalytic β subunit of GGTase2, RabG...

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Publicat a:Nat Struct Mol Biol
Autors principals: Kuchay, Shafi, Wang, Hui, Marzio, Antonio, Jain, Kunj, Homer, Harrison, Fehrenbacher, Nicole, Philips, Mark R., Zheng, Ning, Pagano, Michele
Format: Artigo
Idioma:Inglês
Publicat: 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6609460/
https://ncbi.nlm.nih.gov/pubmed/31209342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-019-0249-3
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