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Studying metabolic flux adaptations in cancer through integrated experimental-computational approaches
The study of tumorigenic rewiring of metabolic flux is at the heart of cancer metabolic research. Here, we review two widely used computational flux inference approaches: isotope tracing coupled with Metabolic Flux Analysis (13C-MFA) and COnstraint-Based Reconstruction and Analysis (COBRA). We descr...
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| Publicado en: | BMC Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2019
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6609376/ https://ncbi.nlm.nih.gov/pubmed/31272436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-019-0669-x |
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