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Spatial-fluxomics provides a subcellular-compartmentalized view of reductive glutamine metabolism in cancer cells
The inability to inspect metabolic activities within subcellular compartments has been a major barrier to our understanding of eukaryotic cell metabolism. Here, we describe a spatial-fluxomics approach for inferring metabolic fluxes in mitochondria and cytosol under physiological conditions, combini...
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| Udgivet i: | Nat Commun |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6430770/ https://ncbi.nlm.nih.gov/pubmed/30903027 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09352-1 |
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