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Autocrine STAT3 activation in HPV positive cervical cancer through a virus-driven Rac1—NFκB—IL-6 signalling axis

Persistent human papillomavirus (HPV) infection is the leading cause of cervical cancer. Although the fundamental link between HPV infection and oncogenesis is established, the specific mechanisms of virus-mediated transformation are not fully understood. We previously demonstrated that the HPV enco...

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Pubblicato in:PLoS Pathog
Autori principali: Morgan, Ethan L., Macdonald, Andrew
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608985/
https://ncbi.nlm.nih.gov/pubmed/31226168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007835
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