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ET-63 TARGETING THE EGFR-STAT-NF-κB AXIS IN GLIOBLASTOMA
Amplification of the epidermal growth factor receptor (EGFR) is observed in ∼50% of glioblastoma tumors. Half of EGFR-amplified tumors in-turn harbor the EGFRvIII mutant, a tumor-associated allele of EGFR which signals constitutively in the absence of ligand. We have previously shown that EGFR and E...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4218160/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.60 |
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