Contribution of promoter DNA sequence to heterochromatin formation velocity and memory of gene repression in mouse embryo fibroblasts

Durable gene silencing through the formation of compact heterochromatin domains plays a critical role during mammalian development in establishing defined tissues capable of retaining cellular identity. Hallmarks of heterochromatin gene repression are the binding of heterochromatin protein 1 (HP1),...

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Bibliographic Details
Published in:PLoS One
Main Authors: Vignaux, Patricia A., Bregio, Celyn, Hathaway, Nathaniel A.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608945/
https://ncbi.nlm.nih.gov/pubmed/31269077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0217699
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