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Heterochromatin formation in the mouse embryo requires critical residues of the histone variant H3.3
In mammals, oocyte fertilisation by sperm initiates development. This is followed by epigenetic reprogramming of both parental genomes, which involves de-novo establishment of chromatin domains. In the mouse embryo, methylation of histone H3(1) establishes an epigenetic asymmetry and is predominant...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3701880/ https://ncbi.nlm.nih.gov/pubmed/20676102 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb2089 |
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