Mutant Huntingtin Affects Cortical Progenitor Cell Division and Development of the Mouse Neocortex

A polyglutamine expansion in huntingtin (HTT) causes the specific death of adult neurons in Huntington's disease (HD). Most studies have thus focused on mutant HTT (mHTT) toxicity in adulthood, and its developmental effects have been largely overlooked. We found that mHTT caused mitotic spindle...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Molina-Calavita, Maria, Barnat, Monia, Elias, Salah, Aparicio, Esther, Piel, Matthieu, Humbert, Sandrine
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608303/
https://ncbi.nlm.nih.gov/pubmed/25057205
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0715-14.2014
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados