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Mutant Huntingtin Affects Cortical Progenitor Cell Division and Development of the Mouse Neocortex
A polyglutamine expansion in huntingtin (HTT) causes the specific death of adult neurons in Huntington's disease (HD). Most studies have thus focused on mutant HTT (mHTT) toxicity in adulthood, and its developmental effects have been largely overlooked. We found that mHTT caused mitotic spindle...
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| Publicado en: | J Neurosci |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Society for Neuroscience
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608303/ https://ncbi.nlm.nih.gov/pubmed/25057205 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0715-14.2014 |
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