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Huntingtin Regulates Mammary Stem Cell Division and Differentiation

Little is known about the mechanisms of mitotic spindle orientation during mammary gland morphogenesis. Here, we report the presence of huntingtin, the protein mutated in Huntington’s disease, in mouse mammary basal and luminal cells throughout mammogenesis. Keratin 5-driven depletion of huntingtin...

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Dettagli Bibliografici
Autori principali: Elias, Salah, Thion, Morgane S., Yu, Hua, Sousa, Cristovao Marques, Lasgi, Charlène, Morin, Xavier, Humbert, Sandrine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3986500/
https://ncbi.nlm.nih.gov/pubmed/24749073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2014.02.011
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