ATP Hydrolysis Is Critically Required for Function of Ca(V)1.3 Channels in Cochlear Inner Hair Cells via Fueling Ca(2+) Clearance

Sound encoding is mediated by Ca(2+) influx-evoked release of glutamate at the ribbon synapse of inner hair cells. Here we studied the role of ATP in this process focusing on Ca(2+) current through Ca(V)1.3 channels and Ca(2+) homeostasis in mouse inner hair cells. Patch-clamp recordings and Ca(2+)...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Weiler, Simon, Krinner, Stefanie, Wong, Aaron B., Moser, Tobias, Pangršič, Tina
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2014
Assuntos:
Brief Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608114/
https://ncbi.nlm.nih.gov/pubmed/24828638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4990-13.2014
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