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Harmonin enhances voltage-dependent facilitation of Ca(v)1.3 channels and synchronous exocytosis in mouse inner hair cells
Ca(v)1.3 channels mediate Ca(2+) influx that triggers exocytosis of glutamate at cochlear inner hair cell (IHC) synapses. Harmonin is a PDZ-domain-containing protein that interacts with the C-terminus of the Ca(v)1.3 α(1) subunit (α(1)1.3) and controls cell surface Ca(v)1.3 levels by promoting ubiqu...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Science Inc
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3717226/ https://ncbi.nlm.nih.gov/pubmed/23613530 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.254367 |
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