Developmental refinement of hair cell synapses tightens the coupling of Ca(2)(+) influx to exocytosis

Cochlear inner hair cells (IHCs) develop from pre-sensory pacemaker to sound transducer. Here, we report that this involves changes in structure and function of the ribbon synapses between IHCs and spiral ganglion neurons (SGNs) around hearing onset in mice. As synapses matured they changed from hol...

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Detalhes bibliográficos
Main Authors: Wong, Aaron B, Rutherford, Mark A, Gabrielaitis, Mantas, Pangršič, Tina, Göttfert, Fabian, Frank, Thomas, Michanski, Susann, Hell, Stefan, Wolf, Fred, Wichmann, Carolin, Moser, Tobias
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2014
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989618/
https://ncbi.nlm.nih.gov/pubmed/24442635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387110
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