Developmental refinement of hair cell synapses tightens the coupling of Ca(2)(+) influx to exocytosis

Cochlear inner hair cells (IHCs) develop from pre-sensory pacemaker to sound transducer. Here, we report that this involves changes in structure and function of the ribbon synapses between IHCs and spiral ganglion neurons (SGNs) around hearing onset in mice. As synapses matured they changed from hol...

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Detaylı Bibliyografya
Asıl Yazarlar: Wong, Aaron B, Rutherford, Mark A, Gabrielaitis, Mantas, Pangršič, Tina, Göttfert, Fabian, Frank, Thomas, Michanski, Susann, Hell, Stefan, Wolf, Fred, Wichmann, Carolin, Moser, Tobias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Publishing Ltd 2014
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Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989618/
https://ncbi.nlm.nih.gov/pubmed/24442635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/embj.201387110
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