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ATP Hydrolysis Is Critically Required for Function of Ca(V)1.3 Channels in Cochlear Inner Hair Cells via Fueling Ca(2+) Clearance

Sound encoding is mediated by Ca(2+) influx-evoked release of glutamate at the ribbon synapse of inner hair cells. Here we studied the role of ATP in this process focusing on Ca(2+) current through Ca(V)1.3 channels and Ca(2+) homeostasis in mouse inner hair cells. Patch-clamp recordings and Ca(2+)...

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Podrobná bibliografie
Vydáno v:J Neurosci
Hlavní autoři: Weiler, Simon, Krinner, Stefanie, Wong, Aaron B., Moser, Tobias, Pangršič, Tina
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6608114/
https://ncbi.nlm.nih.gov/pubmed/24828638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4990-13.2014
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