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Frontline Science: Sphingosine rescues burn‐injured mice from pulmonary Pseudomonas aeruginosa infection
Burn patients with concomitant pulmonary Pseudomonas aeruginosa (PA) infection have mortality rates as high as 50%, despite antibiotic therapy. Sphingosine is generated from ceramide via ceramidase and has been reported to have antimicrobial properties. We observed a reduction in sphingosine and a c...
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| Veröffentlicht in: | J Leukoc Biol |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
John Wiley and Sons Inc.
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6608017/ https://ncbi.nlm.nih.gov/pubmed/27418352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI0416-197R |
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