Fibril-induced glutamine-/asparagine-rich prions recruit stress granule proteins in mammalian cells

Prions of lower eukaryotes are self-templating protein aggregates that replicate by converting homotypic proteins into stable, tightly packed beta-sheet–rich protein assemblies. Propagation is mediated by prion domains, low-complexity regions enriched in polar and devoid of charged amino acid residu...

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Udgivet i:Life Sci Alliance
Main Authors: Riemschoss, Katrin, Arndt, Verena, Bolognesi, Benedetta, von Eisenhart-Rothe, Philipp, Liu, Shu, Buravlova, Oleksandra, Duernberger, Yvonne, Paulsen, Lydia, Hornberger, Annika, Hossinger, André, Lorenzo-Gotor, Nieves, Hogl, Sebastian, Müller, Stephan A, Tartaglia, Gian, Lichtenthaler, Stefan F, Vorberg, Ina M
Format: Artigo
Sprog:Inglês
Udgivet: Life Science Alliance LLC 2019
Fag:
Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6607448/
https://ncbi.nlm.nih.gov/pubmed/31266883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.201800280
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