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Asparagine and glutamine ladders promote cross-species prion conversion
Prion transmission between species is governed in part by primary sequence similarity between the infectious prion aggregate, PrP(Sc), and the cellular prion protein of the host, PrP(C). A puzzling feature of prion formation is that certain PrP(C) sequences, such as that of bank vole, can be convert...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5704488/ https://ncbi.nlm.nih.gov/pubmed/28931606 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M117.794107 |
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