Novel oncogene 5MP1 reprograms c-Myc translation initiation to drive malignant phenotypes in colorectal cancer

BACKGROUND: Translational reprogramming through controlled initiation from non-AUG start codons is considered a crucial driving force in tumorigenesis and tumor progression. However, its clinical impact and underlying mechanism are not fully understood. METHODS: Using a bioinformatics approach, we i...

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Veröffentlicht in:EBioMedicine
Hauptverfasser: Sato, Kuniaki, Masuda, Takaaki, Hu, Qingjiang, Tobo, Taro, Gillaspie, Sarah, Niida, Atsushi, Thornton, Mackenzie, Kuroda, Yousuke, Eguchi, Hidetoshi, Nakagawa, Takashi, Asano, Katsura, Mimori, Koshi
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2019
Schlagworte:
Research paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606960/
https://ncbi.nlm.nih.gov/pubmed/31175057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.05.058
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