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(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution
BACKGROUND: In brain, CREB-regulated transcription co-activator 1 (CRTC1) is involved in metabolic dysregulation. In humans a SNP in CRTC1 was associated to body fat percentage and two SNPs affected RNA Pol II binding and chromatin structure, implying epigenetic regulation of CRTC1. We sought to und...
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| Wydane w: | EBioMedicine |
|---|---|
| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Elsevier
2019
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6606956/ https://ncbi.nlm.nih.gov/pubmed/31153815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.05.050 |
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