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(Epi)genetic regulation of CRTC1 in human eating behaviour and fat distribution
BACKGROUND: In brain, CREB-regulated transcription co-activator 1 (CRTC1) is involved in metabolic dysregulation. In humans a SNP in CRTC1 was associated to body fat percentage and two SNPs affected RNA Pol II binding and chromatin structure, implying epigenetic regulation of CRTC1. We sought to und...
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| Gepubliceerd in: | EBioMedicine |
|---|---|
| Hoofdauteurs: | , , , , , , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Elsevier
2019
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6606956/ https://ncbi.nlm.nih.gov/pubmed/31153815 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2019.05.050 |
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