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Tau Secretion: Good and Bad for Neurons

In Alzheimer’s disease (AD), neurofibrillary tangles (NFTs), lesions composed of hyperphosphorylated and aggregated tau, spread from the transentorhinal cortex to the hippocampal formation and neocortex. Growing evidence indicates that tau pathology propagates trans-synaptically, implying that patho...

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Bibliographic Details
Published in:Front Neurosci
Main Authors: Pernègre, Camille, Duquette, Antoine, Leclerc, Nicole
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606725/
https://ncbi.nlm.nih.gov/pubmed/31293374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2019.00649
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