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Similarities and Differences in the Pattern of Tau Hyperphosphorylation in Physiological and Pathological Conditions: Impacts on the Elaboration of Therapies to Prevent Tau Pathology

Tau protein, a neuronal microtubule-associated protein, becomes hyperphosphorylated in several neurodegenerative diseases called tauopathies. Hyperphosphorylation of tau is correlated to its redistribution from the axon to the somato-dendritic compartment at early stages of tauopathies. Interestingl...

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Udgivet i:Front Neurol
Main Authors: Duquette, Antoine, Pernègre, Camille, Veilleux Carpentier, Ariane, Leclerc, Nicole
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7817657/
https://ncbi.nlm.nih.gov/pubmed/33488502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fneur.2020.607680
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