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Chemical logic of MraY inhibition by antibacterial nucleoside natural products

Novel antibacterial agents are needed to address the emergence of global antibiotic resistance. MraY is a promising candidate for antibiotic development because it is the target of five classes of naturally occurring nucleoside inhibitors with potent antibacterial activity. Although these natural pr...

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Detalles Bibliográficos
Publicado en:Nat Commun
Main Authors: Mashalidis, Ellene H., Kaeser, Benjamin, Terasawa, Yuma, Katsuyama, Akira, Kwon, Do-Yeon, Lee, Kiyoun, Hong, Jiyong, Ichikawa, Satoshi, Lee, Seok-Yong
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606608/
https://ncbi.nlm.nih.gov/pubmed/31266949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10957-9
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