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Structural basis of nucleoside and nucleoside drug selectivity by concentrative nucleoside transporters

Concentrative nucleoside transporters (CNTs) are responsible for cellular entry of nucleosides, which serve as precursors to nucleic acids and act as signaling molecules. CNTs also play a crucial role in the uptake of nucleoside-derived drugs, including anticancer and antiviral agents. Understanding...

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Bibliografiska uppgifter
Huvudupphovsmän: Johnson, Zachary Lee, Lee, Jun-Ho, Lee, Kiyoun, Lee, Minhee, Kwon, Do-Yeon, Hong, Jiyong, Lee, Seok-Yong
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4139061/
https://ncbi.nlm.nih.gov/pubmed/25082345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03604
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