A molecular switch from STAT2-IRF9 to ISGF3 underlies interferon-induced gene transcription

Cells maintain the balance between homeostasis and inflammation by adapting and integrating the activity of intracellular signaling cascades, including the JAK-STAT pathway. Our understanding of how a tailored switch from homeostasis to a strong receptor-dependent response is coordinated remains lim...

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Publicat a:Nat Commun
Autors principals: Platanitis, Ekaterini, Demiroz, Duygu, Schneller, Anja, Fischer, Katrin, Capelle, Christophe, Hartl, Markus, Gossenreiter, Thomas, Müller, Mathias, Novatchkova, Maria, Decker, Thomas
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606597/
https://ncbi.nlm.nih.gov/pubmed/31266943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-10970-y
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