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Dasatinib can enhance paclitaxel and gemcitabine inhibitory activity in human pancreatic cancer cells

SRC and its activated form, phospho-SRC (pSRC), are aberrantly activated in pancreatic cancer and SRC represents a potential target for pancreatic cancer therapy. In this paper, we examined the inhibitory effect of dasatinib, a potent SRC inhibitor in combination with paclitaxel or gemcitabine on hu...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Cancer Biol Ther
Main Authors: Ma, Ling, Wei, Jia, Su, Gloria H., Lin, Jiayuh
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6606004/
https://ncbi.nlm.nih.gov/pubmed/30866697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2019.1579956
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