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Defects in the origin licensing checkpoint stresses cells exiting G0

The full licensing of replication origins in late G1 is normally enforced by the licensing checkpoint. In this issue, Matson et al. (2019. J. Cell Biol. https://doi.org/10.1083/jcb.201902143) show that this checkpoint is inoperative in cells exiting from G0, resulting in incomplete origin licensing...

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Vydáno v:J Cell Biol
Hlavní autor: Blow, J. Julian
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605787/
https://ncbi.nlm.nih.gov/pubmed/31266845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201905181
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