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Palladium-catalyzed coupling reactions on functionalized 2-trifluoromethyl-4-chromenone scaffolds. Synthesis of highly functionalized trifluoromethyl-heterocycles
The chromenone core is a ubiquitous group in biologically-active natural products and has been extensively used in organic synthesis. Fluorine derived compounds, including those with a trifluoromethyl group (-CF(3)), have shown enhanced biological activities in numerous pharmaceuticals compared with...
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| Publié dans: | Synthesis (Stuttg) |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605783/ https://ncbi.nlm.nih.gov/pubmed/31274934 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0037-1610669 |
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