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Palladium-catalyzed cross-coupling reaction of alkenyl bromides with potassium alkyltrifluoroborates

The Suzuki-Miyaura-type cross-coupling reaction of potassium alkyltrifluoroborates with various alkenyl bromides in the presence of 10 mol % of PdCl(2)(dppf)·CH(2)Cl(2) and 3.0 equiv of Cs(2)CO(3) in aqueous toluene at 80 °C provided the desired compounds in 49–95% yields. A variety of functional gr...

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Autori principali: Molander, Gary A., Ham, Jungyeob, Seapy, Dave G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1827200/
https://ncbi.nlm.nih.gov/pubmed/18196177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tet.2006.10.088
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