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Early-Onset Epileptic Encephalopathy Caused by Gain-of-Function Mutations in the Voltage Sensor of K(v)7.2 and K(v)7.3 Potassium Channel Subunits
Mutations in K(v)7.2 (KCNQ2) and K(v)7.3 (KCNQ3) genes, encoding for voltage-gated K(+) channel subunits underlying the neuronal M-current, have been associated with a wide spectrum of early-onset epileptic disorders ranging from benign familial neonatal seizures to severe epileptic encephalopathies...
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| Publicado no: | J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society for Neuroscience
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6605567/ https://ncbi.nlm.nih.gov/pubmed/25740509 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4423-14.2015 |
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