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Patterned, But Not Tonic, Optogenetic Stimulation in Motor Thalamus Improves Reaching in Acute Drug-Induced Parkinsonian Rats

High-frequency deep brain stimulation (DBS) in motor thalamus (Mthal) ameliorates tremor but not akinesia in Parkinson's disease. The aim of this study was to investigate whether there are effective methods of Mthal stimulation to treat akinesia. Glutamatergic Mthal neurons, transduced with cha...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Neurosci
Main Authors: Seeger-Armbruster, Sonja, Bosch-Bouju, Clémentine, Little, Shane T.C., Smither, Roseanna A., Hughes, Stephanie M., Hyland, Brian I., Parr-Brownlie, Louise C.
פורמט: Artigo
שפה:Inglês
יצא לאור: Society for Neuroscience 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605530/
https://ncbi.nlm.nih.gov/pubmed/25609635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3277-14.2015
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