Patterned, But Not Tonic, Optogenetic Stimulation in Motor Thalamus Improves Reaching in Acute Drug-Induced Parkinsonian Rats

High-frequency deep brain stimulation (DBS) in motor thalamus (Mthal) ameliorates tremor but not akinesia in Parkinson's disease. The aim of this study was to investigate whether there are effective methods of Mthal stimulation to treat akinesia. Glutamatergic Mthal neurons, transduced with cha...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Seeger-Armbruster, Sonja, Bosch-Bouju, Clémentine, Little, Shane T.C., Smither, Roseanna A., Hughes, Stephanie M., Hyland, Brian I., Parr-Brownlie, Louise C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2015
Onderwerpen:
Brief Communications
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605530/
https://ncbi.nlm.nih.gov/pubmed/25609635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3277-14.2015
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