Loss of the Neuron-Specific F-Box Protein FBXO41 Models an Ataxia-Like Phenotype in Mice with Neuronal Migration Defects and Degeneration in the Cerebellum

The cerebellum is crucial for sensorimotor coordination. The cerebellar architecture not only requires proper development but also long-term integrity to ensure accurate functioning. Developmental defects such as impaired neuronal migration or neurodegeneration are thus detrimental to the cerebellum...

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Vydáno v:J Neurosci
Hlavní autoři: Mukherjee, Chaitali, Holubowska, Anna, Schwedhelm-Domeyer, Nicola, Mitkovski, Miso, Lee, Shih-Ju, Kannan, Madhuvanthi, Matz, Annika, Vadhvani, Mayur, Stegmüller, Judith
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605212/
https://ncbi.nlm.nih.gov/pubmed/26063905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2133-14.2015
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