Loss of the Neuron-Specific F-Box Protein FBXO41 Models an Ataxia-Like Phenotype in Mice with Neuronal Migration Defects and Degeneration in the Cerebellum

The cerebellum is crucial for sensorimotor coordination. The cerebellar architecture not only requires proper development but also long-term integrity to ensure accurate functioning. Developmental defects such as impaired neuronal migration or neurodegeneration are thus detrimental to the cerebellum...

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Publicado no:J Neurosci
Main Authors: Mukherjee, Chaitali, Holubowska, Anna, Schwedhelm-Domeyer, Nicola, Mitkovski, Miso, Lee, Shih-Ju, Kannan, Madhuvanthi, Matz, Annika, Vadhvani, Mayur, Stegmüller, Judith
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6605212/
https://ncbi.nlm.nih.gov/pubmed/26063905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2133-14.2015
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