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Fbxo41 Promotes Disassembly of Neuronal Primary Cilia

Neuronal primary cilia are signaling organelles with crucial roles in brain development and disease. Cilia structure is decisive for their signaling capacities but the mechanisms regulating it are poorly understood. We identify Fbxo41 as a novel Skp1/Cullin1/F-box (SCF) E3-ligase complex subunit tha...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: King, Cillian R., A. A. Quadros, Ana R., Chazeau, Anaël, Saarloos, Ingrid, van der Graaf, Anne Jolien, Verhage, Matthijs, Toonen, Ruud F.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2019
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546786/
https://ncbi.nlm.nih.gov/pubmed/31160656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44589-2
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