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Fbxo41 Promotes Disassembly of Neuronal Primary Cilia

Neuronal primary cilia are signaling organelles with crucial roles in brain development and disease. Cilia structure is decisive for their signaling capacities but the mechanisms regulating it are poorly understood. We identify Fbxo41 as a novel Skp1/Cullin1/F-box (SCF) E3-ligase complex subunit tha...

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Publicado en:Sci Rep
Main Authors: King, Cillian R., A. A. Quadros, Ana R., Chazeau, Anaël, Saarloos, Ingrid, van der Graaf, Anne Jolien, Verhage, Matthijs, Toonen, Ruud F.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6546786/
https://ncbi.nlm.nih.gov/pubmed/31160656
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-44589-2
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