Blocking the Interaction between EphB2 and ADDLs by a Small Peptide Rescues Impaired Synaptic Plasticity and Memory Deficits in a Mouse Model of Alzheimer's Disease

Soluble amyloid-β (Aβ) oligomers, also known as Aβ-derived diffusible ligands (ADDLs), are thought to be the key pathogenic factor in Alzheimer's disease (AD), but there is still no effective treatment for preventing or reversing the progression of the disease. Targeting NMDA receptor trafficki...

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Opis bibliograficzny
Wydane w:J Neurosci
Główni autorzy: Shi, Xiao-Dong, Sun, Kai, Hu, Rui, Liu, Xiao-Ya, Hu, Qiu-Mei, Sun, Xiao-Yu, Yao, Bin, Sun, Nan, Hao, Jing-Ru, Wei, Pan, Han, Yuan, Gao, Can
Format: Artigo
Język:Inglês
Wydane: Society for Neuroscience 2016
Hasła przedmiotowe:
Research Articles
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604917/
https://ncbi.nlm.nih.gov/pubmed/27881781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1327-16.2016
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