Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model

Alzheimer's disease (AD) is a progressive neurodegenerative disease, which affects more and more people. But there is still no effective treatment for preventing or reversing the progression of the disease. Soluble amyloid-beta (Aβ) oligomers, also known as Aβ-derived diffusible ligands (ADDLs)...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Hu, Rui, Wei, Pan, Jin, Lu, Zheng, Teng, Chen, Wen-Yu, Liu, Xiao-Ya, Shi, Xiao-Dong, Hao, Jing-Ru, Sun, Nan, Gao, Can
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386541/
https://ncbi.nlm.nih.gov/pubmed/28358367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2017.140
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