Extension of Helix 12 in Munc18-1 Induces Vesicle Priming

Munc18-1 is essential for vesicle fusion and participates in the docking of large dense-core vesicles to the plasma membrane. Recent structural data suggest that conformational changes in the 12th helix of the Munc18-1 domain 3a within the Munc18-1:syntaxin complex result in an additional interactio...

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Publicado en:J Neurosci
Main Authors: Munch, Anders S., Kedar, Girish H., van Weering, Jan R. T., Vazquez-Sanchez, Sonia, He, Enqi, André, Timon, Braun, Thimo, Söllner, Thomas H., Verhage, Matthijs, Sørensen, Jakob B.
Formato: Artigo
Idioma:Inglês
Publicado: Society for Neuroscience 2016
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604893/
https://ncbi.nlm.nih.gov/pubmed/27358447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0007-16.2016
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