Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors

Cholinergic vulnerability, characterized by loss of acetylcholine (ACh), is one of the hallmarks of Alzheimer's disease (AD). Previous work has suggested that decreased ACh activity in AD may contribute to pathological changes through global alterations in alternative splicing. This occurs, at...

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Vydáno v:J Neurosci
Hlavní autoři: Kolisnyk, Benjamin, Al-Onaizi, Mohammed A., Xu, Jason, Parfitt, Gustavo M., Ostapchenko, Valeriy G., Hanin, Geula, Soreq, Hermona, Prado, Marco A. M., Prado, Vania F.
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604881/
https://ncbi.nlm.nih.gov/pubmed/27277805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4614-15.2016
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