Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors

Cholinergic vulnerability, characterized by loss of acetylcholine (ACh), is one of the hallmarks of Alzheimer's disease (AD). Previous work has suggested that decreased ACh activity in AD may contribute to pathological changes through global alterations in alternative splicing. This occurs, at...

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Gepubliceerd in:J Neurosci
Hoofdauteurs: Kolisnyk, Benjamin, Al-Onaizi, Mohammed A., Xu, Jason, Parfitt, Gustavo M., Ostapchenko, Valeriy G., Hanin, Geula, Soreq, Hermona, Prado, Marco A. M., Prado, Vania F.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604881/
https://ncbi.nlm.nih.gov/pubmed/27277805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4614-15.2016
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