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Cholinergic Regulation of hnRNPA2/B1 Translation by M1 Muscarinic Receptors

Cholinergic vulnerability, characterized by loss of acetylcholine (ACh), is one of the hallmarks of Alzheimer's disease (AD). Previous work has suggested that decreased ACh activity in AD may contribute to pathological changes through global alterations in alternative splicing. This occurs, at...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Kolisnyk, Benjamin, Al-Onaizi, Mohammed A., Xu, Jason, Parfitt, Gustavo M., Ostapchenko, Valeriy G., Hanin, Geula, Soreq, Hermona, Prado, Marco A. M., Prado, Vania F.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2016
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6604881/
https://ncbi.nlm.nih.gov/pubmed/27277805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4614-15.2016
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